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. 2019 Aug 16;19:199. doi: 10.1186/s12872-019-1183-3

Table 3.

Summary of recommendations on treatment of obstetric-associated venous thromboembolism

ACCP [12] ANZJOG [15] ASH [16] ESC [19] GTH [20] RCOG [24] SOGC [26]
Pregnant patients
Anticoagulant choice

LMWH, UFH

NOACs(×)

LMWH, UFH, VKA (×) LMWH (prefer), UFH

UFH (high risk)

LMWH (low risk)

LMWH (prefer), UFH

VKA (×), NOACs (×)

LWMH LMWH, VKA (×, unless special situation), NOACs (×)
Duration 3 m 6-8 m 3 m 6w-3 m 3 m
Mechanical prophylaxis Compression stocking 2y
Vena cava filters Acute DVT with contra-indications for anticoagulation Patients with iliac vein VTE, with proven DVT and recurrent PE Acute DVT with contra-indications for anticoagulation
Thrombolysis Only life-threatening DVT Not recommend Only life-threatening PE Massive PE Only life-threatening DVT
Delivery patients Discontinuation of LMWH at least 24 h Intravenous UFH for 24 h
Lactating women
Anticoagulant choice VKA, UFH, LMWH Warfarin, LMWH LMWH, Warfarin (X)
Duration 6w 6w 6w 6w-3 m 6w

ACCP American College of Chest Physicians, ANZJOG Australian and New Zealand Journal of Obstetrics and Gynaecology, ASH American Society of Hematology, DVT Deep Vein Thrombosis, ESC European Society of Cardiology, GTH Working Group in Women’s Health of the Society of Thrombosis and Haemostasis, LMWH Low Molecular Weight Heparin, NOAC Novel Oral Anticoagulants, PE Pulmonary Embolism, RCOG Royal College of Obstetricians and Gynaecologists, SOGC Society of Obstetricians and Gynaecologists of Canada, UFH Unfraction Heparin, VKA Vitamin K antagonist