Table 3.

Comparison of OR, sensitivity, specificity, PPV, NPV, concordance, and κ coefficient with 95% CI between Cryo and TBB according to PD-L1 expression

	PD-L1 ≥ 50% (95% CI)	PD-L1 ≥ 1% (95% CI)
OR	45 (1.394–1452)	2 (0.244–16.37)
Sensitivity	66.7% (0.094–0.992)	44.4% (0.137–0.788)
Specificity	100% (0.753–1)	71.4% (0.290–0.963)
PPV	100% (0.158–1)	66.7% (0.223–0.957)
NPV	92.9% (0.661–0.998)	50% (0.187–0.813)
Concordance	93.8% (0.698–0.998)	56.3% (0.299–0.803)
κ coefficient	0.7647 (0.288–1)	0.1515 (0–0.608)

OR odds ratio, PPV positive predict value, NPV negative predict value, CI confidence interval, Cryo cryobiopsy, TBB transbronchial biopsy, PD-L1 programmed death ligand 1