Table 2.
Baseline characteristics and clinical features of hemodialysis patients with and without infectious spondylitis (model 2)
| Variables | Patients with infectious spondylitis (n = 16) | Patients without infectious spondylitis (n = 64) | p value |
|---|---|---|---|
| Age, mean ± SD, year | 60.9 ± 12.0 | 61.0 ± 11.5 | 0.98 |
| Male Gender, n (%) | 7 (43.8%) | 22 (34.4%) | 0.48 |
| Diabetes mellitus, n (%) | 6 (37.5%) | 22 (34.4%) | 0.82 |
| Hypertension, n (%) | 8 (50%) | 51 (79.7%) | 0.02 |
| Coronary artery diseases, n (%) | 3 (18.8%) | 9 (14.1%) | 0.64 |
| Heart failure, n (%) | 1 (6.3%) | 10 (15.6%) | 0.33 |
| Cerebral vascular diseases, n (%) | 1 (6.3%) | 6 (9.4%) | 0.69 |
| Liver cirrhosis, n (%) | 2 (12.5%) | 4 (6.3%) | 0.40 |
| Malignancy, n (%) | 1 (6.3%) | 8 (12.5%) | 0.48 |
| Immunosuppression status, n (%) | 1 (6.3%) | 0 (0%) | 0.04 |
| Degenerative spinal disease, n (%) | 14 (87.5%) | 3 (4.7%) | < 0.001 |
| History of spinal operation, n (%) | 1 (6.3%) | 3 (4.7%) | 0.80 |
| Primary cause of ESRD | 0.73 | ||
| Chronic Glomerulonephritis | 7 (43.8%) | 37 (57.8%) | |
| Diabetic nephropathy | 6 (37.5%) | 15 (23.4%) | |
| Polycystic kidney disease | 2 (12.5%) | 9 (14.1%) | |
| Malignant hypertension | 1 (6.3%) | 2 (3.1%) | |
| Others | 0 (0%) | 1 (1.6%) | |
| HD vintage (years) | 4.65 ± 4.36 | 5.03 ± 3.59 | 0.42 |
| HD access | |||
| Arteriovenous fistula | 6 (37.5%) | 53 (82.8%) | < 0.001 |
| Arteriovenous graft | 3 (18.8%) | 7 (10.9%) | 0.40 |
| Tunneled cuffed catheter | 7 (43.8%) | 4 (6.3%) | < 0.001 |
| Access operation within recent 6 months | 10 (62.5%) | 9 (14.1%) | < 0.001 |
| Laboratory data (blood sample) | |||
| Leukocyte count, 1000/μL | 7.53 ± 2.2 | 6.57 ± 2.2 | 0.13 |
| Hemoglobin, g/dL | 8.86 ± 1.3 | 9.82 ± 1.3 | 0.012 |
| RDW, % | 16.3 ± 2.2 | 14.2 ± 1.4 | < 0.001 |
| Platelet Count, 1000/μL | 181 ± 76 | 198 ± 68 | 0.37 |
| BUN, mg/dL | 68.2 ± 27.8 | 65.4 ± 18.7 | 0.62 |
| Creatinine, mg/dL | 9.10 ± 3.15 | 10.1 ± 2.4 | 0.18 |
| Potassium, mEq/L | 4.60 ± 0.74 | 4.79 ± 0.77 | 0.36 |
| Calcium, mg/dL | 9.54 ± 1.08 | 9.81 ± 0.95 | 0.34 |
| Inorganic phosphorus, mg/dL | 4.98 ± 1.99 | 5.07 ± 1.52 | 0.84 |
| ALT, U/L | 18.2 ± 13.2 | 15.3 ± 11.1 | 0.20 |
| ALP, U/L | 139.9 ± 79.7 | 84.5 ± 45.0 | 0.001 |
| Albumin, g/dL | 3.35 ± 0.65 | 3.97 ± 0.42 | < 0.001 |
| Glucose AC, mg/dL | 149 ± 86 | 124 ± 70 | 0.07 |
| hsCRP, mg/L | 29.90 ± 47.02 | 8.18 ± 16.85 | 0.024 |
| Ferritin, ng/mL | 475.7 ± 513.2 | 419.9 ± 485.3 | 0.85 |
ESRD end stage renal disease, HD hemodialysis, RDW red blood cell volume distribution width, ALT alanine transaminase, ALP alkaline phosphatase, BUN blood urea nitrogen, AC ante cibum, hsCRP high sensitivity C- reactive protein