Table 1.
Summary of Clinical and CT Imaging Characteristics of Type 1 AIP Patients with PaT
PDAC (n = 3) | SEP (n = 1) | CCa (n = 1) |
|||
---|---|---|---|---|---|
Case 1a | Case 2 | Case 3 | |||
Gender | Male | Male | Female | Female | Female |
Surveillance period (month) | 3 | 0 | 0 | 3 | 6 |
IgG4 (≤2 g/L, g/L) | 6.9 | 5.2 | 4.6 | 0.3 | 4.1 |
CA-199 (0-35 U/ml, U/ml) | 64.7 | 14.6 | 106.0 | 2.0 | 21.4 |
Biopsy at initial visit | |||||
Location | Pancreas | Pancreas | Pancreas | Pancreas | Pancreas |
Evidence of PaT | No | Yes | Yes | No | No |
Presence of extrapancreatic involvement | |||||
Bile duct | No | No | Yes | Yes | Yes |
Kidney | No | No | No | No | No |
Retroperitoneum | No | Yes | No | Yes | No |
CT imaging characteristics of pancreatic parenchyma | |||||
Focal enlargement | Yes | Yes | Yes | Yes | Yes |
Presence of atrophy | No | No | Yes | No | No |
Presence of heterogeneity | Yes | Yes | Yes | Yes | Yes |
Presence of low-density | Yes | Yes | Yes | Yes | Yes |
Mass-like | Yes | Yes | Yes | No | Yes |
Relative density | |||||
Arterial phase | Hypo | Hypo | Hypo | Hypo | Hypo |
Venous phase | Hypo | Hypo | Hypo | Hypo | Iso |
Absolute density (Hu) | |||||
Pre-enhanced phase | 38 | 45 | 28 | 45 | 45 |
Arterial phase | 53 | 51 | 32 | 76 | 89 |
Venous phase | 68 | 81 | 37 | 94 | 94 |
CT imaging characteristics of main pancreatic duct | |||||
Dilatation | Yes | No | No | No | No |
Cutoff | Yes | No | Yes | No | No |
CT imaging characteristics of peripancreatic structures | |||||
Presence of halo sign | Yes | No | No | Yes | No |
Presence of stranding | Yes | No | Yes | Yes | No |
Presence of ascites | No | No | No | Yes | No |
Presence of vessel stricture | Yes | Yes | Yes | Yes | No |
Abbreviations: AIP autoimmune pancreatitis, PaT pancreatic tumor, PDAC pancreatic ductal adenocarcinoma, SEP solitary extramedullary plasmacytoma, CC cholangiocarcinoma, Hypo hypoattenuating, Iso Isoattenuating, Hu Hounsfield
a Marked cases underwent pancreatic resection, and the presence of concurrent PaT in other unmarked cases were proved by biopsy at the initial visit or in the surveillance period