Table 2.
Comparison of Clinical and CT imaging Characteristics between Type 1 AIP Patients with and without PaT
AIP (n = 69) | AIP + PaC (n = 5) | P Value | |
---|---|---|---|
Male | 58 (84%) | 2 (40%) | 0.044 |
Age (year) | 61 (24–80) | 58 (42–76) | 0.845 |
Surveillance period (month) | 5 (1–109) | 3 (0–6) | 0.086 |
IgG4 (n = 65) | 0.561 | ||
<1 time upper limit | 8 (14%) | 1 (20%) | |
1–2 times upper limit | 11 (17%) | 0 (0%) | |
≥ 2 times upper limit | 41 (69%) | 4 (80%) | |
CA-199 (n = 65, U/ml) | 19.5 (2.0–1987.0) | 21.4 (2.0–106.0) | 0.767 |
Biopsy at the initial visit | 41 (58%) | 5 (100%) | 0.150 |
Presence of extrapancreatic involvement | |||
Bile duct | 63 (91%) | 3 (60%) | 0.087 |
Kidney | 25 (36%) | 0 (0%) | 0.160 |
Retroperitoneum | 9 (9%) | 2 (40%) | 0.157 |
CT imaging characteristics of pancreatic parenchyma | |||
Enlargement pattern | 0.003 | ||
Diffuse | 49 (71%) | 0 (0%) | |
Focal | 20 (29%) | 5 (100%) | |
Presence of atrophy | 10 (15%) | 1 (20%) | 0.564 |
Presence of heterogeneity | 28 (41%) | 5 (100%) | 0.015 |
Presence of low-density (n = 26) | 21 (30%) | 5 (100%) | 0.004 |
Mass-like low-density | 6 (29%) | 4 (80%) | 0.055 |
Relative density of low-density | |||
Arterial phase | 1.000 | ||
Hypoattenuating | 21 (100%) | 5 (100%) | |
Isoattenuating | 0 (0%) | 0 (0%) | |
Hyperattenuating | 0 (0%) | 0 (0%) | |
Venous phase | 0.562 | ||
Hypoattenuating | 14 (67%) | 4 (80%) | |
Isoattenuating | 7 (33%) | 1 (20%) | |
Hyperattenuating | 0 (0%) | 0 (0%) | |
Absolute density of low-density (Hu) | |||
Pre-enhanced phase | 42 (33–53) | 45 (28–45) | 0.769 |
Arterial phase | 71 (51–96) | 53 (32–89) | 0.313 |
Venous phase | 83 (57–112) | 81 (37–94) | 0.255 |
CT imaging characteristics of main pancreatic duct | |||
Presence of dilatation | 16 (23%) | 1 (20%) | 1.000 |
Presence of cutoff | 31 (45%) | 2 (40%) | 1.000 |
CT imaging characteristics of peripancreatic structures | |||
Presence of halo sign | 43 (62%) | 2 (40%) | 0.374 |
Presence of stranding | 14 (20%) | 3 (60%) | 0.076 |
Presence of ascites | 2 (3%) | 1 (20%) | 0.192 |
Presence of vessel stricture | 44 (64%) | 4 (80%) | 0.651 |
Abbreviations: AIP autoimmune pancreatitis, PaT pancreatic tumor, Hu Hounsfield
Quantitative data are expressed as median (range), qualitative data as absolute values (percentages)