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. 2019 Aug 16;38:360. doi: 10.1186/s13046-019-1368-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — CBP treatments induce apoptosis in mesothelioma cells. FACS analysis by Annexin V-FITC/PI double staining assay for the detection of apoptosis in MSTO, NCI and Mes-2 cells treated with 20 μM CPB for 24, 48 and 72 h. Q2 and Q4: early and late apoptotic cells; Q1: necrotic fraction; Q3: live cells. Histograms on the right report a data summary of the apoptotic index. Bars represent the average ± SD of independent experiments (n = 3). Statistically significant difference compared to untreated cells: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. CTRL: untreated cells