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. Author manuscript; available in PMC: 2020 Aug 8.
Published in final edited form as: Mol Cell. 2019 Aug 8;75(3):576–589.e5. doi: 10.1016/j.molcel.2019.07.008

Figure 7.

Figure 7.

Model for the sequential reactions of Pol IV, RDR2 and DCL3, collectively accounting for siRNA biogenesis and RNA channeling in the RNA-directed DNA methylation pathway. Related information pertaining to Pol IV sequences that may influence activity is provided in Figure S7.