Table 1.

Normality of vitamin D, MMP-9 and TIMP-1 levels in COPD subjects, healthy smokers and healthy non-smokers

	COPD (n = 26)	Healthy Smoker (n = 25)	Healthy Non- Smoker n = 27)	p-value
Vitamin D 25(OH)D (ng/mL)
Mean	21.96	27.87	31.71	< 0.001
Median	21.35	27.44	30.21
SD	6.62	7.08	9.24
Minimum	3.38	17.19	19.97
Maximum	32.72	53.80	60.60
95% CI	19.28 – 24.63	24.95-30.79	28.06-35.37
p (Shapiro-Wilk)	0.35	0.001	0.02
MMP-9(ng/mL)
Mean	11.98	2.23	0.89	0.003
Median	1.74	0.99	0.50
SD	41.54	3.94	1.12
Minimum	0.25	0.21	0.08
Maximum	214	19.7	4.5
95% CI	-4.80-28.76	0.61-3.86	0.44-1.33
p (Shapiro-Wilk)	< 0.001	< 0.001	< 0.001
TIMP-1(ng/mL)
Mean	58.40	24.64	46.54	< 0.001
Median	17.43	5.66	12.6
SD	77.53	57.77	71.48
Minimum	10.66	1.66	0.28
Maximum	297.2	290	327
95% CI	27.09-89.72	0.80-48.49	18.27-74.82
p (Shapiro Wilk)	< 0.001	< 0.001	< 0.001