FIG. 1.

Peripheral immune cell recovery after total-body irradiation. Panels A–D: Total white blood cell, monocyte, lymphocyte and neutrophil counts, respectively, were all acutely depleted by TBI. Monocytes and neutrophils recovered by dau 30 postirradiation while total white blood cells and lymphocytes remained significantly decreased until days 51 and 58 postirradiation, respectively. After recovery, total white blood cells, monocytes and neutrophils in irradiated animals did not differ from controls, but lymphocytes increased above controls animals at day 129 postirradiation and remained elevated thereafter. *P < 0.05, **P < 0.01 and ***P < 0.001.