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. 2019 Aug 13;12:1379–1386. doi: 10.2147/DMSO.S215187

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© 2019 Liang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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Metabolomic analysis of urine samples from the two groups: (A) OPLS-DA model built with training set (green dot, nondepressed T2DM patients after stroke; blue dot, T2DM patients with PSD); (B) T-predicted scatter plot built with validation set (green dot, nondepressed T2DM patients after stroke; blue dot, T2DM patients with PSD); (C) 399-item permutation test.

Abbreviations: T2DM, type 2 diabetes mellitus; PSD, post-stroke depression; OPLS-DA, orthogonal partial least-squares discriminant analysis.