Table 2.
Risk factors for developing acute interstitial nephritis or acute tubular necrosis
| Case | PPIs | NSAIDs | Antibiotics | Chemotherapy (conventional) | Contrast imaging studies | Hypotension | Sepsis | |
|---|---|---|---|---|---|---|---|---|
| Interstitial nephritis | 1 | a | a | a | a | a | None | None |
| 2 | None | None | None | None | None | None | None | |
| 3 | None | None | None | None | 2 mo prior | None | None | |
| 4 | None | None | None | None | 2 wk prior | None | None | |
| 5 | Omeprazole | None | None | Carboplatin | 2 mo prior | None | None | |
| 6 | Omeprazole | None | None | None | 1 mo prior | None | None | |
| 7 | a | a | a | Carboplatin 6 mo prior |
a | None | None | |
| 8 | Omeprazole | None | None | None | 1 mo prior | None | None | |
| 9 | a | a | a | Carboplatin 9 mo prior |
a | None | None | |
| No interstitial nephritis | 10 | None | None | Amoxicillin 10 days prior | None | 1 mo prior | None | None |
| 11 | Pantoprazole | None | Cefazolin 2 mo prior |
None | None | None | None | |
| 12 | a | Naproxen | None | None | Recent | None | None | |
| 13 | Pantoprazole | None | Fluconazole | None | 1 mo prior | None | None | |
| 14 | None | None | None | None | 3 wk prior | None | None | |
| 15 | Omeprazole | None | None | None | None | None | None | |
NSAIDs, nonsteroidal anti-inflammatory drugs; PPI, proton pump inhibitors.
a
Data unavailable.