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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Curr Opin Chem Biol. 2019 Mar 12;51:18–29. doi: 10.1016/j.cbpa.2019.01.023

Figure 2.

Figure 2.

The structures of two synthetic small molecule activators of SIRT6’s deacetylase activities. One of them, UBCS039 is shown to bind the fatty acyl pocket of SIRT6.