Methods |
Adequate allocation generation, double‐blind, no ITT |
Participants |
Army recruits, USA |
Interventions |
Rifampin: 4 x 600 mg versus placebo |
Outcomes |
Eradication, failure serogroup of eradication failure
Follow‐up: 11 days |
Notes |
Data extracted for 1) all (regardless of carrier status), 2) for carriers only, 3) for non‐carriers only. Main serogroup: Y |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Low risk |
Adequate allocation generation |
Allocation concealment (selection bias) |
Unclear risk |
Unclear |
Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
Double‐blind |
Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No ITT |
Selective reporting (reporting bias) |
Low risk |
No evidence |
Other bias |
Low risk |
No evidence |