Dowd 1966.
Methods | Double‐blind, no ITT | |
Participants | Army recruits, USA | |
Interventions | Ampicillin: 30 x 500 mg versus oral penicillin G: 30 x 462 mg versus placebo | |
Outcomes | Eradication, serogroup of eradication failure, resistance developed Follow‐up: 26 days | |
Notes | Main serogroup: B | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | Unclear |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Double‐blind |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | No ITT |
Selective reporting (reporting bias) | Low risk | No evidence |
Other bias | Low risk | No evidence |