Methods |
Cluster‐randomisation by households, open, no ITT |
Participants |
Household contacts, Saudi Arabia |
Interventions |
IM ceftriaxone 1 x 250 mg or 125 mg for children versus rifampin: 4 x 600 mg or 10 mg/kg versus none |
Outcomes |
Eradication, acquisition in non‐carriers
Follow‐up: 2 weeks |
Notes |
Data presented for carriers. Serogroup A |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Allocation concealment (selection bias) |
Unclear risk |
Unclear |
Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Open |
Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Open |
Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No ITT |
Selective reporting (reporting bias) |
Low risk |
No evidence |
Other bias |
Low risk |
No evidence |