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. 2013 Oct 25;2013(10):CD004785. doi: 10.1002/14651858.CD004785.pub5

Simmons 2000.

Methods Open, no ITT
Participants Household contacts, New Zealand
Interventions Rifampicin: 600 mg, children > 1 month, 10 mg/kg versus IM ceftriaxone: 250 mg < 12 years, 125 mg
Outcomes Morbidity, eradication, eradication of serogroup B, adverse effects
 Follow‐up: 6 days
Notes Data presented for carriers. Main serogroup: B
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk Unclear
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Open
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Open
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No ITT
Selective reporting (reporting bias) Low risk No evidence
Other bias Low risk No evidence

f/u: follow‐up
 IM: intramuscular
 ITT: intention‐to‐treat