Table 1.
Variables | No. | PD-L1 | p | HIF1α | p | ||
---|---|---|---|---|---|---|---|
Positive | Negative | Positive | Negative | ||||
Total | 85 | 57 | 28 | 64 | 21 | ||
Age (years) | 0.885 | 0.856 | |||||
<45 | 48 | 32 | 16 | 37 | 11 | ||
≥45 | 37 | 25 | 12 | 27 | 10 | ||
Sex | 0.159 | 0.880 | |||||
Male | 32 | 18 | 14 | 26 | 6 | ||
Female | 53 | 39 | 14 | 41 | 12 | ||
Tumor size (mm3) | 0.010* | 0.055 | |||||
≥40 | 57 | 44 | 13 | 47 | 10 | ||
<40 | 28 | 13 | 15 | 17 | 11 | ||
T Stage | 0.030* | 0.084 | |||||
T1 and T2 | 49 | 38 | 11 | 33 | 16 | ||
T3 | 36 | 19 | 17 | 31 | 5 | ||
Lymphocytic thyroiditis | 0.219 | 0.051 | |||||
Yes | 39 | 23 | 16 | 25 | 14 | ||
No | 46 | 34 | 12 | 39 | 7 | ||
TNM | 0.005** | 0.002** | |||||
Ⅰ+Ⅱ | 47 | 38 | 9 | 42 | 5 | ||
Ⅲ+Ⅳ | 38 | 19 | 19 | 22 | 16 | ||
Metastasis | 0.000*** | 0.000*** | |||||
Yes | 35 | 15 | 20 | 18 | 17 | ||
No | 50 | 42 | 8 | 46 | 4 | ||
Psammoma body | 0.914 | 0.268 | |||||
Yes | 12 | 5 | 7 | 7 | 5 | ||
No | 73 | 52 | 21 | 57 | 16 | ||
Calcification in stoma | 0.442 | 0.116 | |||||
Yes | 43 | 31 | 12 | 36 | 7 | ||
No | 42 | 26 | 16 | 28 | 14 | ||
PD-L1 | 0.000*** | ||||||
Positive | 67 | 59 | 8 | ||||
Negative | 18 | 5 | 13 |
Note: *p<0.05, **p<0.01, ***p<0.001.
Abbreviations: HIF-1α, hypoxia-inducible factor 1α; PD-L1, programmed cell death-1 protein ligand 1.