Table 2.

Plasma TFV concentration and social relationships scales stratified by HPTN 067 site, daily dosing arm participants, (Weeks 18 and 30 data combined; 161 participants, n=302 records), July 2012-May, 2014.

Variable	Cape Town (n=103)	Bangkok (n=106)	Harlem (n=93)	Overall (n=302)
Mean TFV concentration ng/ml, SD (min, max)	71.8, 108.2 (BLQ, 476)	81.7, 81.4 (BLQ, 419)*	81.0, 132.2 (BLQ, 743)	78.1, 107.9 (BLQ, 743)
Low Perceived External Support for PrEP Scale Proportion (95% Confidence Interval)
0 barriers/items reported	68.9% (59.2, 77.2)	80.2% (71.4, 86.8)	77.4% (67.6, 84.9)	75.5% (70.2, 80.0)
1 barrier/item reported	9.7% (5.2, 17.2)	3.8% (1.4, 9.7)	5.4% (2.2, 12.5)	6.3% (4.0, 9.7)
2 barriers/items reported	21.4% (14.4, 30.4)	16.0% (10.1, 24.4)	17.2% (10.7, 26.5)	18.2% (14.2, 23.0)
Participant-Staff Disclosure Challenges Scale* Proportion (95% Confidence Interval)
0 barriers/items reported	57.3% (47.4, 66.6)	73.6%* (64.2, 81.2)	83.9%* (74.8, 90.1)	71.2% (65.8, 76.0)
1 barrier/item reported	10.7% (5.9, 18.4)	11.3% (6.4, 19.0)	7.5% (3.6, 15.1)	9.9% (7.0, 13.9)
2 barriers/items reported	16.5% (10.4, 25.1)	12.3% (7.2, 20.1)	6.5% (2.9, 13.8)	11.9% (8.7, 16.1)
3 barriers/items reported	4.9% (2.0, 11.3)	1.9% (0.05, 7.3)	1.1% (0.1, 7.5)	2.7% (1.3, 5.2)
4 barriers/items reported	10.7% (6.0, 18.4)	0.9% (0.1, 6.6)	1.1% (0.1, 7.5)	4.3% (2.5, 7.3)

^*p<0.01 as compared to Cape Town; SD refers to the Standard Deviation; BLQ refers to “Below the Limit of Quantification”