Table 4.

Multivariable regressions of statistically significant univariate analysis variables on plasma TFV Concentration among HPTN 067 daily dosing arm participants (All Sites; Weeks 18/30 Data Combined; 161 participants, n=302 records) , July 2012-May, 2014.

	Exponentiated Adjusted Coefficient	95% Confidence Interval	p-value
Low Perceived External Support for PrEP Scale (Range: 0-2)	0.86	0.59- 1.25	p=0.42
Participant-Staff Disclosure Challenges Scale (Range 0-4)	0.62	0.46- 0.84	p=0.002
Self-report days since last dose	0.73	0.65- 0.83	p≤0.001

Model covariates are: age, education, problematic substance abuse, low perceived control over HIV infection, staff judge patient; staff have negative reactions to PrEP pill taking, study site, study-related side effects, weight, creatinine clearance.