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. 2019 Aug 7;10:552. doi: 10.3389/fendo.2019.00552

Table 2.

Correlation with clinic-pathological features and presence of distant metastasis at the diagnosis.

Total (59) M1 (10) M0-x (49) p-value
Gender 0.03
    M 16/59 (27%) 6/16 (37.5%) 10/16 (62.5%)
    F 43/59 (73%) 4/43 (9.3%) 39/43 (90.7%)
Age (average) 14.40 12.50 ± 2.75 14.89 ± 2.44 0.01
Tumor size (median; mm) 20.0 30 21 0.08
T 0.0007
    1 19/59 (21.7%) 0/19 (0%) 19/19 (100%)
    2 8/59 (13.6%) 1/8 (12.5%) 7/8 (87.5%)
    3 26/59 (44.1%) 4/26 (15.4%) 22/26 (84.6%)
    4 6/59 (10.2%) 5/6 (83.3%) 1/6 (16.7%)
Extrathyroidal extension 0.10
    Yes 25/59 (42.3%) 8/25 (32.0%) 17/25 (68%)
    No 34/59 (57.7%) 2/34 (5.9%) 32/34 (94.1%)
Multifocality 0.13
    Yes 25/59 (42.3%) 7/25 (28%) 18/25 (72%)
    No 34/59 (57.7%) 3/34 (8.8%) 31/34 (91.1%)
Vascular invasion 0.28
    Yes 48/59 (71.2%) 10/48 (20.8%) 38/48 (79.2%)
    No 11/59 (6.7%) 0/11 (0%) 11/11 (100%)
Lymph nodal metastasis 0.02
    N0 and N1a 30/59 (50.8%) 2/30 (6.7%) 28/30 (93.3%)
    N1b 20/59 (33.9%) 7/20 (35.0%) 13/20 (65%)
    Nx 9/59 (15.3%) 1/9 (11.1%) 8/9 (88.9%)

F, female; M, male.

Bold values are the statistically significant associations.