Table 2.

Association between breast cancer and fracture incidence (multivariate Cox regression models).

Age group	Breast cancer vs. no cancer	Breast cancer with tamoxifen vs. no cancer	Breast cancer without endocrine therapy vs. no cancer
	OR (95% CI)* and p-values	OR (95% CI)* and p-values	OR (95% CI)* and p-values
Total	2.39 (1.70–3.34)	2.67 (1.58–4.53)	1.63 (0.80–3.33)
	P <0.001	P < 0.001	p = 0.181
Age 18–30	1.06 (0.07–16.86)	0.00	2.08 (0.13–33.22)
	0.970		p = 0.605
Age 31–40	3.98 (1.16–13.68)	2.66 (1.18–5.98)	2.12 (0.87–5.17)
	p = 0.028	p = 0.018	p = 0.098
Age 41–50	2.25 (1.35–3.75)	2.48 (1.64–3.76)	2.02 (1.15–3.56)
	p = 0.002	P < 0.001	p = 0.015

^⁎multivariable Cox regression adjusted for BMI, smoking behavior, comorbidities, and corticosteroid therapy.