Table 4.
Size exclusion chromatography (SEC) analyses with percent monomer of concentrated proteins.
| Sample Name | Release (%) | Week 1 (%) | Week 2 (%) | Week 4 (%) |
|---|---|---|---|---|
| IgG1 | 100.0 | 100.0 | 99.6 | 99.4 |
| IgG1 FES | 100.0 | 100.0 | 100.0 | 99.0 |
| IgG1σ | 100.0 | 100.0 | 99.7 | 99.3 |
| IgG2 | 98.17 | 98.0 | 97.9 | 97.7 |
| IgG2σ | 100.0 | 100.0 | 99.2 | 100.0 |
| IgG4 PAA | 100.0 | 99.6 | 99.5 | 99.5 |
| IgG4σ1 | 98.0 | 97.9 | 97.7 | 97.5 |
| IgG4σ2 | 97.8 | 97.9 | 97.7 | 97.4 |
Representative data of SEC analysis. Abbreviations: IgG1 AA, IgG1 L234A/L235A; IgG1 FES, IgG1 L234F/L235E/P331S; IgG4 PAA, IgG4 S228P/F234A/L235A.