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Mass spectrometry analysis of serum-incubated ADCs. (a) A07-108-T289C SG3544; (b) A07-108 T289C SG3249; (c) A07-108-T289C SG3683; and, (d) A07-108-T289C SG3376. All of the samples were analyzed immediately after addition to serum (control), after incubation in rat serum for seven days at 37 °C, and after incubation in mouse serum for seven days at 37 °C. All of the spectra are zoomed in to show the heavy-chain only.
