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. 2017 Oct 25;6(4):16. doi: 10.3390/antib6040016
Aa amino acids
ADC antibody-drug conjugate
ADCC antibody-dependant cell-mediated cytotoxicity
APO apoptosis antigen
Bcl-2 B-cell lymphoma 2, apoptosis inhibitor
BsAbs bispecific antibodies
CARs chimeric antibody receptors
CD cluster of differentiation
CDC complement-dependent cellular cytotoxicity
c-FLIP cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
CPT-TRAIL circularly permuted TRAIL
DC dendritic cell
DcR decoy receptor
DcR1 decoy receptor 1, TRAIL-R3
DcR2 decoy receptor 2, TRAIL-R4
DD death domain
DISC death-inducing signaling complex
DR death receptor
DR4 death receptor 4, TRAIL-R1
DR5 death receptor 5, TRAIL-R2
Fab fragment antigen-binding
Fas fibroblast associated surface antigen
Fas-L as ligand
Fc crystalized fragment
FcR crystalized fragment receptor
GPI glycosylphosphatidylinisotol
KD Kringle domain
Mcl-1 myeloid cell leukemia-1
moAbs monoclonal antibodies
NK cell natural killer cell
OPG steoprotegerin, TRAIL-R5
PBLs eripheral blood cells
ROS reactive oxygen species
rhTRAIL human recombinant TRAIL
scFv single chain fragment variable
sc-TRAIL single chain TRAIL
sTRAIL soluble TRAIL
TNC-TRAIL tenascin-C-TRAIL
TNF tumor necrosis factor
TNF-α tumor necrosis factor alpha
TRAIL TNF-related apoptosis-inducing ligand