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. Author manuscript; available in PMC: 2019 Aug 19.
Published in final edited form as: Nat Genet. 2019 May 31;51(6):957–972. doi: 10.1038/s41588-019-0407-x

Fig. 4 |. credible set size plotted against variant posterior probability for 3,655 sNPs in 253 99% credible sets according to variant annotation.

Fig. 4 |

a, Exonic variants. SNPs are marked by triangles, with triangle size proportional to CADD score. Red triangles indicate missense SNPs mapping to small credible sets (≤5 SNPs) or to sets containing SNPs with high individual PP of driving the association signal (>50%). b, SNPs with regulatory potential. Symbol color corresponds to regulatory potential as derived from DNase I hypersensitivity analysis in target tissues (Methods). Annotation was restricted to variants with PP>1%; SNPs with PP≥90% contained in credible sets with ≤10 SNPs are labeled. Data are plotted as credible set size (x axis) against variant PP(y axis). Blue and green color coding for gene and SNP labels refers to kidney-function relevance and has the same meaning as in Fig. 2.