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. Author manuscript; available in PMC: 2019 Aug 19.
Published in final edited form as: Brain Behav Immun. 2018 Feb 1;69:532–539. doi: 10.1016/j.bbi.2018.01.012

Figure 1. Experimental timeline.

Figure 1.

A) In experiment 1, minocycline (45mg/kg/day; or water alone) was administered beginning 7 days after TBI or sham injury and continuing until the day of tissue collection. Beginning 10 days after injury, ethanol was presented in a 2-bottle choice test every other day. B) In experiment 2, minocycline (or water control) was administered on days 7–14 after injury. On day 14, mice were treated with a single IP injection of ethanol (2g/kg) or saline control, and tissue (brain and blood) were collected 2 hours later.