. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: Can J Ophthalmol. 2018 Aug 24;54(2):242–246. doi: 10.1016/j.jcjo.2018.05.013

Table 1:

Clinical characteristics of patients with optic neuritis by orbital MRI result

Characteristic	MRI Positive^a (n=77)	MRI Negative (n=15)	OR (95% CI); P value
Female n (%)	56 (72.7%)	11 (73.3%)	0.97 (0.28–3.38; 0.96
Age median (IQR)	38.0 (31.9–50.3)	39.7 (26.5–46.261)	1.03 (0.98–1.08); 0.25
Caucasian n (%)	62 (80.5%)	15 (100%)
Affected eye			1.25 (0.41–3.85); 0.70
Right n (%)	35 (45.5%)	6 (40.0%)
Presence of pain	59 (76.6%)	7 (46.7%)	3.75 (1.19–11.75); 0.023
Presenting visual function
Mean visual acuity (SD)	1.011 (0.981)	0.606 (0.601)	1.78 (0.74–4.31); 0.20
Visual field mean deviation (SD)	−14.2 (8.09)	−13.5 (10.4)	0.99 (0.92–1.07); 0.81
Presence of disc edema	23 (29.9%)	6 (40.0%)	0.64 (0.20–2.00); 0.44
Days to MRI mean (SD)	13.0 (8.2)	11.8 (7.8)	1.02 (0.95–1.09); 0.59
Visual function at final follow-up visit
Mean visual acuity (SD)	0.153 (0.334)	0.117 (0.209)	1.52 (0.16–14.90); 0.72
Visual field mean deviation (SD)	−4.99 (5.11)	−2.97 (2.64)	0.87 (0.71–1.07); 0.18

^a.

Orbital MRI was considered “positive” if the optic nerve on the affected side demonstrated high T2 signal within the nerve or post-contrast enhancement on T1 weighted sequences.