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. 2019 Jun 20;25(9):1030–1041. doi: 10.1111/cns.13184

Figure 4.

Figure 4

L‐glutamine promoted astrocytes proliferation, activated STAT3 pathway, and upregulated BDNF via HSP70 in vivo. A, Triple staining of Ki67 (red) and GFAP (green) and CD31 (violet) in the saline, L‐glutamine, and L‐glutamine + AZ groups. Bar = 100 μm/40 μm. B, The quantitative analysis of the number of Ki67+/GFAP+ cells. C, Western blot analysis of p‐STAT3, STAT3, and BDNF expression in the sham, saline, L‐glutamine, and L‐glutamine + AZ groups. Quantitative analysis of p‐STAT3 (D) and BDNF (E). N = 5 per group. Data are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001