Table 1.
Univariate and multivariate analysis of OS in CGGA RNA sequencing dataset, GBM
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| TMEM71 expression | 7.035 (1.571‐31.494) | 0.011 | 18.43 (2.463‐138.02) | 0.005 |
| Age at diagnosis | 1.005 (0.988‐1.022) | 0.569 | – | – |
| Gender | 1.227 (0.795‐1.893) | 0.355 | – | – |
| TCGA subtype | 1.082 (0.900‐1.301) | 0.403 | – | – |
| IDH mutation status | 0.685 (0.406‐1.157) | 0.157 | – | – |
| MGMT methylation | 0.564 (0.364‐0.872) | 0.01 | 0.921 (0.506‐1.673) | 0.786 |
| Radiotherapy | 0.412 (0.259‐0.654) | <0.001 | 0.498 (0.274‐0.907) | 0.023 |
| Chemotherapy | 0.336 (0.214‐0.528) | <0.001 | 0.442 (0.251‐0.778) | 0.005 |
| KPS | 0.970 (0.955‐0.986) | <0.001 | 0.961 (0.942‐0.981) | <0.001 |