Figure 1.

Changes induced by DMF treatment on T‐ and B‐lymphocyte subpopulations. Representation of percentages (%) of central memory (CCR7⁺ CD45RA⁻), effector memory (CCR7⁻ CD45RA⁻), and naïve (CCR7⁺ CD45RA⁺) subpopulations from CD4⁺ and CD8⁺ T lymphocytes (A and B, respectively); and % of preswitched memory (CD27⁺ IgD⁺), class‐switched (CD27⁺ IgD⁻) and (CD27⁻ IgD⁺) naïve CD19⁺ B lymphocytes (C), before the treatment (baseline) and after 1, 3, 6 and, 12 months of follow‐up. Data are expressed as mean SD. Each dot represents the value of an individual (n = 22). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001