Graphic summary of randomized controlled trials demonstrating caries arrest after
topical treatment with silver diamine fluoride (SDF). Studies are arranged vertically by
frequency of SDF application. Caries arrest is defined as the fraction of initially
active carious lesions that became inactive and firm to a dental explorer. SDF (38%
unless noted otherwise); GIC, glass ionomer cement; NaF, 5% sodium fluoride varnish; +
OHI q6mon, SDF every year and oral hygiene instructions every 6 mo; q1year, every year;
q3mon, every 3 mo; q6mon, every 6 mo. Updated from Horst et al. (2016).