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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Am J Med Genet A. 2019 Feb;179(2):224–236. doi: 10.1002/ajmg.a.61003

Figure 1:

Figure 1:

Flowchart of patient enrollment detailing the data exclusion and final sample sizes used in different analyses for individuals with A) Smith–Magenis syndrome (SMS; top) and Sibling (SIB; bottom) controls. Data excluded from AES study (*) for noncompliance (2SMS; 1SIB) or incomplete data (8SMS; 9SIB). Reasons for incomplete AES data included missing log; watch off/on; data not retrievable; and/or lost watch. Data excluded from 24-h Tb study (**) for incomplete data (9SMS; 2 SIB). Subjects (3SMS; 5SIB) enrolled after the end of AES data collection period provided Tb data only.