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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Am J Med Genet A. 2019 Feb;179(2):224–236. doi: 10.1002/ajmg.a.61003

Table III:

Age Comparison of AES in SMS and SIBS

P
Under 10 years SMS (n=24)a,b SIB (n=8) (SMS vs. SIB)c
Gender 11F/13M 5F/3M 0.6851
Mean age (y) 5.1 ± 1.8 5.4y ± 1.6 0.6785
Age range (y) 2–9 3–7
Total Night Sleep (mins) 465.7 ± 48.7 534.2 ± 18.9 0.0006
Sleep Efficiency (%) 78.6 ± 17.5 87.8 ± 2.9 0.1534
Sleep Onset (hh:mm) 20:45 ± 0:59 21:16 ± 1:06b 0.2251
Waking Onset (hh:mm) 06:15 ± 0:46b 7:25 ± 1:01 0.0018
Waking (WASO, mins) 104.5 ± 33.2b 74.9 ± 18.2 0.0235
Naps (mins) 77.3 ± 51.0 33.0 ± 21.1 0.0245
Total 24-Hour Sleep (mins) 543.0 ± 54.8 567.5 ± 30.0 0.2406
10–15 years SMS (n=7) SIB (n=9)
Gender 5F/2M 5F/4M 0.6329
Mean Age (y) 13.2 ± 1.2 12.3 ± 1.9 0.8250
Age range (y) 11 – 14 10.2 – 15.7
Total Night Sleep (mins) 480.4 ± 54.8 511.4 ± 27.3 0.1594
Sleep Efficiency (%) 76.1 ± 4.9 89.7 ± 2.8 0.0001
Sleep Onset (hh:mm) 20:40 ± 0:30 22:36 ± 1:06 0.0009
Waking Onset (hh:mm) 6:44 ± 0:46 8:07 ± 1:07 0.0156
Waking (WASO, mins) 149.3 ± 28.8 59.1 ± 16.0 0.0001
Naps (mins) 61.2 ± 32.2 36.0 ± 50.9 0.2735
Total 24-Hour Sleep (mins) 541.6 ± 72.8 547.4 ± 73.2 0.8770
16 years and older SMS (n=6) NAd
Gender 2M/4F
Mean Age (y) 19.9 ± 2.9
Age range (y) 16 – 24
Total Night Sleep (mins) 473.4 ± 81.8
Sleep Efficiency (%) 81.7 ± 9.2
Sleep Onset (hh:mm) 20:40 ± 0:46
Waking Onset (hh:mm) 6:57 ± 0:28
Waking (WASO, mins) 113.5 ± 49.7
Naps (mins) 120.16 ± 77.4
Total 24-Hour Sleep (mins) 593.6 ± 148.8
a

Mean values +/− SD are given for age and sleep parameters.

b

SMS within-group sleep differences by age significant only for waking onset (<10y and >16y; p=.0453); and WASO (<10y and 10–15y; p=.0031

c

Between-group (SMS vs. SIB) differences determined by Fisher’s exact test (gender) or unpaired 2-tailed t-test (age and AES sleep data).

d

NA= No available SIB control group for age 16y and over.

Abbreviations: M, male; F, female; y, years; mins, minutes; WASO, waking after sleep onset.