Table 3.
Antibiotic resistance enzymes and genotypic screening of six resistant Klebsiella pneumonia and Enterobacter cloacae isolates.
| Strain | Carbapenemase | Size of plasmids harboring carbapenemase-encoding genes | ESBL | BSBL | 16S rRNA methylase | AmpC variant | Aminoglycoside-modifying enzyme (acetyltransferase) | Quinolone resistance enzymes | MLST |
|---|---|---|---|---|---|---|---|---|---|
| KP-Q1 | NDM-1 | 70 kb | CTX-M-3 | TEM-1, OXA-1 | RmtC | - | AAC(6′)-Ib | QnrB | ST152 |
| KP-Q2 | NDM-1 | 70 kb | CTX-M-57 | TEM-1, OXA-1 | RmtC | - | AAC(6′)-Ib | QnrB | ST152 |
| KP-Q3 | NDM-1 | 70 kb | CTX-M-82 | TEM-1, OXA-1 | RmtC | - | AAC(6′)-Ib | QnrB | ST152 |
| KP-Q4 | NDM-1 | 70 kb | CTX-M-15 | TEM-1, OXA-1 | - | - | AAC(6′)-Ib | - | ST572 |
| EN.C.Q5 | VIM-1 | 60 kb | - | TEM-1 | - | CMY-4 | - | - | ST171 |
| EN.C.Q6 | VIM-1 | 150 kb | - | - | - | - | AAC(6′)-Ib | - | ST73 |
KP: Klebsiella pneumoniae
EN.C: Enterobacter cloacae
ESBL: Extended-spectrum β-lactamase
MLST: Multilocus sequence typing