Table 2.
Body weights and blood glucose levels.
| Index | Group | Initial | 4 weeks | 16weeks |
|---|---|---|---|---|
| Body weight (g) | Control | 459.30±19.13 | 511.70±18.18 | 625.00±27.67 |
| DM | 466.81±19.69 | 512.09±22.20 | 527.66±36.75∗ | |
| Sildenafil | 443.44±17.89 | 471.33±25.26 | 494.75±52.82 | |
| EULE (0.5%) | 433.55±24.06 | 498.77±17.57 | 541.66±26.17 | |
| EULE (1%) | 465.60±15.85 | 493.10±19.15 | 514.75±65.13 | |
| EULE (2%) | 478.00±16.62 | 511.30±16.32 | 576.20±17.32 | |
|
| ||||
| Blood glucose (mmol/L) | Control | 7.10±0.21 | 5.75±0.18 | 5.11±0.21 |
| DM | 18.94±1.51∗∗ | 13.3±2.17∗ | 12.26±1.47∗ | |
| Sildenafil | 18.39±1.25∗∗∗ | 15.56±1.79∗ | 14.61±1.58∗ | |
| EULE (0.5%) | 20.66±1.60∗∗∗ | 15.36±2.63∗∗ | 14.77±1.21∗ | |
| EULE (1%) | 18.80±0.82∗∗∗ | 14.72±1.60∗∗ | 15.34±1.77∗∗ | |
| EULE (2%) | 20.59±1.69∗∗∗ | 12.44±2.15∗∗ | 12.17±1.34∗∗ | |
Initial: before drug administration. 4 weeks: after drug administration for 4 weeks. 16 weeks: after drug administration for 16 weeks. Control, normal control group; DM, diabetic model group; sildenafil, diabetic group treated with sildenafil; EULE (0.5%), diabetic group treated with 0.5% EULE; EULE (1%), diabetic group treated with 1% EULE; EULE (2%), diabetic group treated with 2% EULE. Data are expressed in mean ± SEM. ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001versus control group (n = 10 in each group).