Figure 1.

Heatmap and volcano plot exhibited the DEGs. (a) Heatmap of the top 40 DEGs between SCR-AGS and HIF-1α-KD-AGS (20 upregulated genes and 20 downregulated genes). Red: upregulated genes; blue: downregulated genes. (b) Volcano plot of the differentially expressed mRNAs between SA and paracarcinoma tissues. Red indicates high expression and green indicates low expression (|log⁡2FC| >1 and adjusted P value < 0.05). DEGs were calculated by edgeR. 53 high expressed DEGs and 31 low expressed ones. This volcano plot was conducted by the ggplot2 package of R language.