Table 1. Demographic profile of studied patients and transplant variables.
| Variables | Stable n = 13 | DGF n = 33 | AR n = 9 | p |
|---|---|---|---|---|
| Age (years; mean±SD) | 48.3±12.2 | 46.8±14.5 | 42.8±11.6 | 0.632* |
| Sex (male/female) | 9/4 | 15/18 | 4/5 | 0.318** |
| Race (white/nonwhite) | 11/2 | 28/5 | 8/1 | 0.950** |
| Donor age (years; mean+SD) | 45.6±10.4 | 46±16.9 | 42.8±17 | 0.864* |
| Donor sex (male/female) | 4/9 | 17/16 | 4/5 | 0.444** |
| Early graft dysfunction (yes/group total) | 9/4 | 29/4 | 7/2 | 0.434** |
| HLA mismatches (A, B, DR; mean+SD) | 2.53±0.5 | 2.2±0.8 | 2.5±0.5 | 0.252* |
| Last PRA (%; median (IQR)) | ||||
| Class I | 1 (0-23.5)a | 7.0 (0-21.5)a | 11 (0-24.1)a | 0.430* |
| Class II | 2 (0-28.5)a | 1.5 (0-22)a | 2.5 (0-24)a | 0.930* |
| Initial immunosuppression (n; %) | 0.069** | |||
| No induction | 6 (46.2) | 10 (30.3) | 4 (44.4) | 0.518* |
| Rabbit anti-thymocyte globulin | 1 (7.7.) | 16 (50) | 4 (44.4) | 0.029* |
| Basiliximab | 6 (46.2) | 6 (18.8) | 1 (11.1) | 0.091* |
| Cold ischemia time (h; mean+ SD) | 20+5.1 | 25.2+7.7 | 21.8+7.4 | 0.196* |
| Underlying renal disease (n; %) | 0.509** | |||
| Unknown | 6 (46.2) | 7 (22.6) | 4 (50) | 0.165* |
| HTN | 5 (38.5) | 13 (39.4) | 4 (44.4) | 0.955* |
| DM | 3 (23.1) | 8 (24.2) | 0 (0) | 0.259* |
| HTN+DM | 1 (8.3) | 4 (12.5) | 0 (0) | 0.554* |
| APKD | 2 (16.7) | 4 (12.5) | 1 (12.5) | 0.934* |
| Other | 0 (0) | 8 (25.8) | 2 (25) | 0.147* |
| Serum Creatinine at Biopsy (mg/dL; mean ± SD) | 2.5±1.9a | 5.7±4b | 3.8±3.3ab | 0.022* |
| Time to biopsy (days; median [IQR]) | 99 [86-116]b | 14 [12-26]a | 58 [14-331]ab | 0.001*** |
SD: standard deviation; HLA: human leukocyte antigen; HTN: hypertension; DM: diabetes mellitus; APKD: autosomal dominant polycystic kidney disease;
*
Analysis of variance (ANOVA);
**
Pearson's chi-square;
***
Kruskal-Wallis test;
a,b
Equal letters do not differ by the Tukey's (ANOVA) or Dunn's (Kruskal-Wallis) tests at the 5% level of significance.