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Changes in heart rate (a), mean arterial pressure (b), lactate (c), and pH (d) during hemorrhagic shock and resuscitation in the three treatment groups, hemorrhagic shock + placebo, hemorrhagic shock + Alda-1 treatment, and sham. BL: baseline; BD: blood withdrawn; PR: postresuscitation. ∗P<0.05, hemorrhagic shock + placebo versus hemorrhagic shock + Alda-1; #P<0.05, hemorrhagic shock + placebo versus sham; $P<0.05, hemorrhagic shock + Alda-1 versus sham.
