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. Author manuscript; available in PMC: 2019 Aug 19.
Published in final edited form as: Sci Immunol. 2019 Jun 28;4(36):eaau6426. doi: 10.1126/sciimmunol.aau6426

Fig. 4. CD86 is up-regulated on the APCs of hypertensive mice.

Fig. 4.

C57BL/6 mice were sham-treated (NT) or Ang Il-treated (HT) for 2 weeks. (A) Surface CD80 and CD86 expression on splenic DCs and peritoneal macrophages (Mφ). Surface expression of CD86 by Kupffer cells was also measured. The representative histograms are shown. (B) DCs and macrophages from naive mice were stimulated in vitro with or without 10 μM Ang II overnight, and surface CD86 expression was measured. (C) Mice were either sham-treated or treated with Ang II and hydralazine (Hyd) for 14 days. Surface CD86 expression was measured in splenic DCs and peritoneal macrophages. Data are means ± SEM. **P < 0.01; ***P < 0.005.