5. Pooled sensitivity and specificity of the conventional polymerase chain reaction (PCR) overall meta‐analysis and the sensitivity analyses.
Analysis | Sensitivity (95% CI) | Specificity (95% CI) |
Overall meta‐analysis PCR | 70% (37% to 90%) | 95% (75% to 99%) |
Exclusion of studies at 'high risk of bias' for patient selection | 76% (31% to 96%) | 91% (60% to 98%) |
Exclusion of studies at 'high risk of bias' for reference standard | 87% (44% to 98%) | 97% (60% to 100%) |
Exclusion of studies that reported the use of antibiotics | 71% (34% to 92%) | 93% (71% to 99%) |
Meta‐analysis with the lower MAT threshold dataset | 70% (36% to 90%) | 95% (75% to 99%) |
Exclusion of studies that were only reported as abstracts | 74% (40% to 93%) | 96% (74% to 99%) |
CI: confidence intervals; MAT: microscopic agglutination test.