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. 2019 Jul 31;2019(7):CD006936. doi: 10.1002/14651858.CD006936.pub4

Summary of findings 2. Motivational interviewing in addition to other smoking cessation treatment for smoking cessation.

Motivational interviewing in addition to other smoking cessation treatment for smoking cessation
Patient or population: tobacco smokers (general population, low income, inpatients and outpatients with mixed diagnoses)
 Setting: community, hospital, healthcare clinics (Australia, Brazil, South Africa, USA)
 Intervention: motivational interviewing in addition to other smoking cessation (SC) treatment
 Comparison: other smoking cessation treatment alone
Outcomes Anticipated absolute effects* (95% CI) Relative effect
 (95% CI) № of participants
 (studies) Certainty of the evidence
 (GRADE) Comments
Risk with other SC treatment only Risk with MI in addition to other SC treatment
Smoking cessation at ≥ 6 months follow‐up Study population RR 1.07
 (0.85 to 1.36) adjusted N = 4167
 (12 RCTs) ⊕⊕⊝⊝
 LOW 1, 2, 3  
15 per 100 16 per 100
 (13 to 20)
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 
 CI: Confidence interval; RR: Risk ratio; OR: Odds ratio;
GRADE Working Group grades of evidenceHigh certainty: We are very confident that the true effect lies close to that of the estimate of the effect
 Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
 Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
 Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

1 Five studies judged to be at high risk of bias, however sensitivity analysis suggested this is unlikely to impact on the result ‐ not downgraded

2 Downgraded one level due to inconsistency: study effects differed across studies, demonstrated by moderate unexplained statistical heterogeneity (I2 = 47%)

3 Downgraded one level due to imprecision: the upper and lower limits of the confidence intervals included both meaningful benefit and harm