. 2019 Jun 27;294(33):12432–12443. doi: 10.1074/jbc.RA119.007945

Table 1.

Fitting parameters for in vivo ERG recordings and statistical analysis of the differences among selected groups

R_max, maximal response amplitude (μV); I_0.5, half-saturating light intensity (cd·s/m²); n, Hill coefficient. Four eyes of two mice of each genotype were recorded for P22 and P36, and six eyes of three mice of each genotype were recorded at P47. p values were calculated to determine the statistical significance between the curve fits for each genotype using an F test. KO, knockout.

	Scotopic b-wave								Scotopic a-wave					Photopic b-wave
	R_max,1	I_0.5,1	n₁	R_max,2	I_0.5,2	n₂	R²	p value	R_max	I_0.5	n	R²	p value	R_max	I_0.5	n	R²	p value
P22
WT	484 ± 86	0.0004 ± 0.0003	0.8 ± 0.4	461 ± 113	2.0 ± 1.5	0.8 ± 0.4	0.8842	<0.0001	482 ± 12	0.59 ± 0.09	0.7 ± 0.07	0.9767	<0.0001	191 ± 5	1.9 ± 0.3	1.1 ± 0.1	0.9743	0.0005
KO	299 ± 184	0.0005 ± 0.0007	0.9 ± 0.9	550 ± 320	3.7 ± 5.7	0.5 ± 0.4	0.8185		406 ± 25	0.80 ± 0.29	0.7 ± 0.14	0.9003		152 ± 9	1.7 ± 0.5	1.3 ± 0.4	0.9026
P36
WT	463 ± 68	0.0002 ± 0.0001	0.9 ± 0.5	531 ± 99	2.0 ± 1.2	0.7 ± 0.3	0.8888	<0.0001	492 ± 15	0.55 ± 0.10	0.7 ± 0.08	0.9667	<0.0001	184 ± 6	1.8 ± 0.3	1.2 ± 0.2	0.9623	<0.0001
KO	156 ± 69	0.0003 ± 0.0005	0.8 ± 0.8	339 ± 125	7.5 ± 7.6	0.6 ± 0.4	0.8764		264 ± 8	0.86 ± 0.17	0.5 ± 0.04	0.9866		75 ± 4	3.5 ± 1.1	1.4 ± 0.3	0.9045
P47
WT	506 ± 55	0.0003 ± 0.0001	1.0 ± 0.4	362 ± 84	1.7 ± 1.3	0.9 ± 0.6	0.7588	<0.0001	445 ± 18	0.49 ± 0.11	0.8 ± 0.12	0.8923	<0.0001	169 ± 8	1.9 ± 0.5	1.4 ± 0.4	0.8788	<0.0001
KO	236 ± 39	0.0007 ± 0.0004	0.8 ± 0.3	231 ± 50	2.8 ± 1.8	0.9 ± 0.4	0.8684		272 ± 8	0.35 ± 0.07	0.7 ± 0.08	0.9432		70 ± 3	2.6 ± 0.7	1.8 ± 0.4	0.9306