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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2019 May 11;105(1):174–182. doi: 10.1016/j.ijrobp.2019.04.038

Table 4.

Outcome in patients treated with breast conservation by use of Regional Nodal Radiation

Pathologic status of axillary nodes Regional Nodal RT No Regional Nodal RT
HR(p) Events/ # Patients 5yr HR(p) Events/ # Patients 5yr
Axillary pCR (ypN0)
LRR 1.00 (ref) 3/62 91.5% (78.8–96.7) 1.66 (0.37–7.40) (0.51) 6/65 94.6% (84.1–98.2)
DS 1.00 (ref) 4/62 90.9% (77.4–96.5) 0.98 (0.26–3.65) (0.98) 4/65 93.3% (83.0–97.4)
OS 1.00 (ref) 5/62 95.5% (83.2–98.9) 0.88 (0.28–2.77) (0.83) 2/65 91.5% (80.8–96.4)
BCSS 1.00 (ref) 2/62 95.5% (83.2–98.9) 0.97 (0.26–3.61) (0.96) 4/65 93.2% (82.8–97.4)
No Axillary pCR (ypN+)
LRR 1.00 (ref) 8/91 90.4% (72.7 – 96.8) 1.55 (0.51–4.75) (0.44) 6/53 90.7% (82.2–95.3)
DS 1.00 (ref) 21/91 72.9% (52.5 – 85.6) 0.88 (0.39–1.93) (0.72) 11/53 74.5% (63.4–82.7)
OS 1.00 (ref) 18/91 82.2% (64.6–91.6) 0.65(0.26–1.60) (0.35) 10/53 79.8% (69.9–86.8)
BCSS 1.00 (ref) 17/91 84.6% (66.9–93.3) 0.63 (0.24–1.68) (0.35) 9/53 80.9% (71.0–87.7)

BCSS, breast cancer-specific survival; DS, disease-free survival; LRR, local-regional recurrence; OS, overall survival