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. Author manuscript; available in PMC: 2020 Aug 19.
Published in final edited form as: Inorg Chem. 2019 Aug 6;58(16):10778–10790. doi: 10.1021/acs.inorgchem.9b01044

Table 4.

(Photo)cytotoxicities and Phototherapeutic Indices of Complexes 1–4 toward SKMEL28 Cells


Cmpd Dark EC50 (μM) Visa EC50 (μM) Vis PI Redb EC50 (μM) Red PI

1 1.12 ± 0.05 0.087 ± 0.006 13 0.590 ± 0.070 2
2 19.5 ± 1.30 0.108 ± 0.002 181 10.5 ± 0.2 2
3 5.53 ± 0.18 0.114 ± 0.019 49 0.270 ± 0.020 21
4 >300 1.13 ± 0.07 >267 12.0 ± 0.4 >25

EC50 values reported ± SEM (μM).

a

400–700 nm, 28 mW cm−2, 100 J cm−2

b

633 nm 28 mW cm−2, 100 J cm−2