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. Author manuscript; available in PMC: 2020 Jul 7.
Published in final edited form as: Drug Metab Rev. 2019 Jul 7;51(2):162–177. doi: 10.1080/03602532.2019.1632891

Figure 6.

Figure 6.

Oxidation of a terminal triple bond with concomitant migration of the hydrogen via a transition state that does not generate an oxirene intermediate. The Fe in a box of nitrogens represents the activated species of cytochrome P450.