. Author manuscript; available in PMC: 2020 Jul 7.

Published in final edited form as: Drug Metab Rev. 2019 Jul 7;51(2):162–177. doi: 10.1080/03602532.2019.1632891

Table 1:

Examples of the time-dependent inhibition of cytochrome P450 by acetylenes involving addition to the prosthetic heme group

Compound	Reference	Compound	Reference
	White 1978; Ortiz de Montellano et al. 1982b		Ortiz de Montellano and Kunze 1980b
	Ortiz de Montellano and Kunze 1981b		Ortiz de Montellano and Kunze 1980b
	White 1978		Ortiz de Montellano and Kunze 1980b
	Ortiz de Montellano et al. 1982a		Ortiz de Montellano and Kunze 1980b
	Ortiz de Montellano and Kunze 1980b		Ortiz de Montellano and Kunze 1980b
	Roberts et al. 1998		Ortiz de Montellano and Kunze 1980b
	Ortiz de Montellano and Kunze 1980b		Ortiz de Montellano et al. 1979
	Rose et al. 1997; Cutler et al. 2000		Fan et al. 2003
	Sharma et al. 1996		Sharma et al. 1996