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. Author manuscript; available in PMC: 2020 Aug 20.
Published in final edited form as: Circulation. 2019 Jun 12;140(8):681–693. doi: 10.1161/CIRCULATIONAHA.119.039642

Figure 2. Genetic ablation of PPP1R3A impairs binding of PP1c to both RyR2 and PLN.

Figure 2.

Representative Western blots and corresponding dot plots showing that with PPP1R3A ablation, (A and B) the association between RyR2 and PP1c is significantly reduced with no change in the association between RyR2 and PP2A, and (C and D) the association between PLN and PP1c is significantly reduced. Data represent mean±SEM and were analyzed using unpaired 2-tailed Student’s t-test. (*P<0.05 vs. WT).