Table 1. Typical settings for IRE in locally advanced pancreatic cancer ⁴ .

Probe spacing range typically used	1.5–2.0 cm
Absolute minimum probe spacing typically used	1.0 cm
Absolute maximum probe spacing typically used	2.6 cm
Default system pulse length for pulse delivery	90 µs
Absolute minimum pulse length typically used	70 µs
Default number of pulses for pulse delivery	70 pulses
Absolute minimum number of pulses typically delivered for each probe pair during pulse delivery	70 pulses
Number of pulses typically delivered between each probe pair during one round of pulse delivery	90–100 pulses
Maximum number of pulses typically delivered for each probe pair after pulse delivery before pull back	180–270 pulses
Default voltage setting	1,500 V/cm
Voltage setting range typically used	1,400–2,000 V/cm
Default maximum voltage output of system	3,000 V
Initial probe exposure typically used for soft tissue (i.e., liver, kidney, lung)	2.0 cm
Initial probe exposure typically used for highly conductive soft tissue (i.e., pancreas)	1.5 cm
Maximum probe exposure typically used for soft tissue	2.5 cm
Pulse timing setting typically used for lesions outside abdominal or thoracic cavities	90 ppm
Pulse timing setting typically reserved for operational verification testing	240 ppm
Default voltage used for test pulse sequence	400 V
Default number of pulses delivered for each probe pair for “test pulse sequence”	1 pulse
Number of pulses typically delivered across each probe pair when performing “tissue conductivity test”	20 pulses
Current range typically displayed after performing a “tissue conductivity test”	20–35 A
Default maximum current limit of NanoKnife	50 A

Abbreviations: A, amperes; IRE, irreversible electroporation; ppm, pulses per minute.