Table 1.
Clinicopatholgical factors according to lymphatic vessel invasion, n (%)
| Variable | n |
Lymphatic vessel invasion |
P value | |
| Absent (n = 289, 65.7%) | Present (n = 151, 34.3%) | |||
| Age (yr) | 440 | 59.86 ± 10.4 | 58.55 ± 11.128 | 0.426 |
| Gender | 0.765 | |||
| Male | 333 (75.7) | 220 (66.1) | 113 (33.9) | |
| Female | 107 (24.3) | 69 (64.5) | 38 (35.5) | |
| Tumor size (cm) | 0.013 | |||
| ≤ 5 | 169 (38.5) | 123 (72.8) | 46 (27.2) | |
| > 5 | 231 (52.5) | 166 (60.4) | 105 (39.6) | |
| Macroscopic type | 0.003 | |||
| Borrmann I-II | 58 (13.2) | 49 (84.5) | 9 (15.5) | |
| Borrmann III | 310 (70.4) | 199 (64.2) | 111 (35.8) | |
| Borrmann IV | 72 (16.4) | 41 (56.9) | 31 (43.1) | |
| Adjacent organs invaded1 | 0.815 | |||
| With | 105 (23.9) | 70 (66.7) | 36 (33.3) | |
| Without | 335 (76.1) | 219 (65.4) | 116 (34.6) | |
| Histologic grade | 0.001 | |||
| Well | 203 (46.1) | 149 (73.4) | 54 (26.6) | |
| Poor | 237 (53.9) | 140 (59.1) | 97 (40.9) | |
| AJCC pT category | 0.002 | |||
| pT2 | 53 (12.0) | 37 (69.8) | 16 (30.2) | |
| pT3 | 136 (31.0) | 104 (76.5) | 32 (23.5) | |
| pT4a | 251 (57.0) | 148 (59.0) | 103 (41.0) | |
| AJCC pN category | 0.000 | |||
| pN0 | 102 (23.2) | 96 (94.1) | 6 (5.9) | |
| pN1 | 71 (16.2) | 51 (71.8) | 20 (28.2) | |
| pN2 | 98 (22.2) | 65 (66.3) | 33 (33.7) | |
| pN3a | 89 (20.2) | 47 (52.8) | 42 (47.2) | |
| pN3b | 80 (18.2) | 30 (37.5) | 50 (62.5) | |
| Resection type | 0.426 | |||
| Proximal | 97 (22.1) | 67 (69.1) | 30 (30.1) | |
| Total | 343 (77.9) | 222 (64.7) | 121 (35.3) | |
| Combined other organ resection | 0.815 | |||
| No | 396 (90.0) | 259 (65.4) | 137 (34.6) | |
| Yes | 44 (10.0) | 30 (68.2) | 14 (31.8) | |
| Survival at 5 yr | 34.2% | 42.5% | 25.1% | 0.000 |
1
Adjacent organs invaded were diagnosed by the surgeon intraoperatively.