Table 2.
Baseline clinical and radiological characteristics
| No. of studies informing characteristic | No. of valid cases informing characteristic (%) | Characteristics | Total | Surgery | SRS | Active monitoring | P | |
|---|---|---|---|---|---|---|---|---|
| 18 | 2050 | N. of patients (%) | 2050 | 560 (27.3) | 450 (22.0) | 1040 (50.7) | ||
| 13 | 803 (39.2) | Mean age, years (SD) | 63.1 (6.9) | 61.5 (4.7) | 54.9 (NR)b | 64 (6.9) | < 0.001 | |
| 17 | 1948 (95.0) | Sex, N (%) | Female | 1549 | 369 (23.8) | 363 (23.4) | 817 (52.7) | 0.539 |
| Male | 399 | 89 (22.3) | 87 (21.8) | 223 (55.9) | ||||
| 16 | 1495 (72.9) | Location, N (%)a | Non-skull base | 1024 | 277 (27.1) | 235 (22.9) | 512 (50.0) | < 0.001 |
| Convexity | 431 | 126 | 86 | 219 | ||||
| Parafalcine | 245 | 61 | 71 | 113 | ||||
| Parasagittal | 151 | 42 | 36 | 73 | ||||
| Tentorial | 62 | 12 | 28 | 22 | ||||
| Intraventricular | 26 | 4 | 12 | 10 | ||||
| Skull base | 471 | 106 (22.5) | 154 (32.7) | 211 (44.8) | ||||
| Anterior midline | 112 | 22 | 43 | 47 | ||||
| Sphenoid wing | 98 | 25 | 11 | 62 | ||||
| Posterior fossa - lateral and posterior | 52 | 23 | 12 | 17 | ||||
| Posterior fossa - midline | 138 | 17 | 87 | 34 | ||||
| 15 | 888 (43.3) | Mean diameter, cm (SD) | 2.14 (0.61) | 2.11 (0.42) | 1.73 (NR)b | 2.19 (0.66) | <0.001 | |
| 10 | 615 (30.0) | Calcification, N (%) | No | 394 | 64 (16.2) | NR | 330 (83.8) | 0.177 |
| Yes | 221 | 27 (12.2) | NR | 194 (87.8) | ||||
| 5 | 298 (14.5) | Tumor signal intensity, N (%) | Hyperintense | 120 | 40 (33.3) | NR | 80 (66.6) | 0.237 |
| Iso/hypointense | 178 | 48 (27.0) | NR | 130 (73.0) | ||||
| 12 | 1107 (54.0) | Peritumoral edema, N (%) | Yes | 144 | 47 (32.6) | 24 (16.7) | 73 (50.7) | |
| No | 963 | 145 (15.1) | 365 (37.9) | 453 (47.0) |
NR not reported, SRS stereotactic radiosurgery
aOne study which dichotomized location into supratentorial and infratentorial was excluded [15]
bAvailable in one study which did not report SD [25]